The beneficial effect of a low glycaemic index diet on blood glucose profiles
Item
- Title
- The beneficial effect of a low glycaemic index diet on blood glucose profiles
- Author(s)
- Adamson Jacqueline
- Abstract
-
Objective
To use the MiniMed Continuous Glucose Monitoring System to investigate the 24-hour blood glucose profile in healthy individuals before and after the introduction of a 7-day low glycaemic index diet. Although low glycaemic index foods have been shown to reduce postprandial hyperglycaemia, there is little information on the long term benefits of a low glycaemic index diet in healthy individuals with good glucose control. Use of the Continuous Glucose Monitoring System is particularly beneficial as glucose readings are taken every 5 minutes throughout the 24-hour period, allowing investigation of blood glucose levels overnight as well as post-prandially.
Design
9 healthy individuals (age 27 ( 1.3 years, BMI 23.7 ( 0.7 kg/m2) completed a 24-hour monitoring period using the Continuous Glucose Monitoring System while consuming their normal diet, and again after consuming a low glycaemic index diet for 7 days.
Results
A reduction in the glycaemic index of their diet occurred during the 24-hour monitoring period (60 ( 2 vs 55 ( 2, p<0.009) in 8 of 9 subjects, while energy and most other macronutrients remained constant. There was a significant increase in fibre intake (14 ( 2 vs 22 ( 2 g/day, p<0.000), but subjects were asked to substitute white bread for a novel low glycaemic index, high fibre bread as part of the dietary modification. There was a significant reduction in fasting glucose at 6am (5.4 ( 0.2 vs 4.3 ( 0.3 mmol/l, p<0.014), mean glucose (5.6 ( 0.2 vs 5.1 ( 0.2 mmol/l, p<0.003), 24-hour AUC glucose (8096 ( 276 vs 7238 ( 234 mmol/l/min, p<0.002) and overnight 8-hour AUC glucose (2684 ( 104 vs 2190 ( 132 mmol/l/min, p<0.02).
Conclusions
This study demonstrates that significant improvements in blood glucose levels can be achieved following a low glycaemic index diet, even in healthy, free living individuals with good blood glucose control. The Continuous Glucose Monitoring System allows identification of blood glucose changes throughout the 24-hour period, which would not be apparent with other methods of blood glucose monitoring. This research has important implications for the use of a low glycaemic index diet in improving blood glucose levels and subsequent insulin demand, thereby helping to prevent conditions such as coronary heart disease and type II diabetes. - presented at
- British College of Osteopathic Medicine
- Date Accepted
- 0
- Date Submitted
- 1.1.1970 00:00:00
- Type
- osteo_thesis
- Language
- English
- Submitted by:
- 62
- Pub-Identifier
- 13618
- Inst-Identifier
- 1076
- Recommended
- 0
- Item sets
- Thesis
Adamson Jacqueline, “The beneficial effect of a low glycaemic index diet on blood glucose profiles”, Osteopathic Research Web, accessed May 3, 2025, https://www.osteopathic-research.org/s/orw/item/1139